It's hard to say... a number of things can affect it. The height of the trailer, the type of trailer (e.g., tilt vs. bunks), the steepness of the ramp...
Generally, with my boat on a bunk trailer, I shoot to just submerge the trailer fenders under the water's surface. If the ramp is steep, I don't back in quite as far. If the ramp is shallow, I have to back in much further, sometimes until my truck's tail pipe is almost under water.
I'd start by submerging your trailer fenders and see how that works.