OK I am going to say, I fall on the side that Muc does, I've used antifreeze every year for 15+ years, raw water cooled in salt water, boat sits on the mooring 6 months of the year no way to flush.
And, when I did the top end rebuild 2 years ago (head gasket failure due to previous overheat), had the 4.3 apart. What I found was surprisingly little rust inside, I wound up replacing the cyl heads not due to rust through behind the valve seats (this is what does in some raw water cooled engines in salt) but due to cracks caused by a previous overheat in 2013. That and the cooling passages were getting eroded from years of salt water cooling. But no failure due to raw water cooling.
The way I look at it:
in the salt pond we coat trailer springs/ubolts/fittings with anti-rust coatings. If you do, they last a very long time. If you don't they look horrible after 5 seasons. Adding the right A/F is to me the same thing. Except you can't see it unless you take off your thermostat housing and look in your intake manifold water passage.
But for freshwater guys, you may not see the same need. However, apparently the manufacturers now do feel that way and have for some time.
as far as antifreeze, I've used either the -100 marine antifreeze or mixed up 50/50 Sierra non tox PG antifreeze. The West stuff is expensive ($12/gallon) the Sierra works out to $7.50/gallon mixed 50/50. The -50 and -60 are not recommended if you get down to zero, if you look at the specs. They are good for mild winters that get down to approx. 20 degrees at the coldest. They get hard at +7 for the -60 and +11 for the -50. The -100 is liquid down to like -45-55*F, almost overkill. The 50/50 mix of Sierra, gives freeze protection to -26*F more than good enough here. Coldest we get is zero.