Depends if it has been run in salt. If shes salty, it may be more trouble than you would think.
Pulling the powerhead is a pain for sure. You will definitely need a hoist with that big powerhead. Will have to separate all of the controls, fuel/oil lines into the motor etc. and separate the lower cowling. If you are lucky you will be able to leave the powerhead fully dressed, but it will tell you, it will surely take some effort to remove the old powerhead gasket from the head and adapter plate. These things are made to adhere when heated so they are really stuck on there.
Once that is up and off, you will have to remove the adapter plate from the midsection, then you can remove the water tube and change the tube, grommet and gasket that is under the adapter plate.
Make sure to get a manual for reassembly. There are some special products that you will need to use upon reassembly, and TORQUE VALUES must be perfect!!! Do NOT attempt this, or even start it without a manual.
Will likely take you a solid weekend of work, maybe two, but very doable for the DIYer that has a motor hoist.